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5 Once steady state is reached, the washout period for AJOVY is similar for monthly and quarterly dosing (~5-6 half-lives) 6 Washout period defined as time until plasma concentrations of AJOVY are below a clinically relevant concentration and thus considered eliminated

Their findings also indicated that tight junction proteins such as, claudin-1, occludin, zonula occludens-1 (ZO-1), mucin 1 and mucin 2 can be more strongly expressed [32]