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In the phase 3 (SURMOUNT-OSA-1 and 2), tirzepatide significantly reduced apneahypopnea index (AHI) over 52 weeks in adults with moderate-to-severe obstructive sleep apnea and obesity, both with and without background PAP therapy
Trial needed to confirm findings Providers and patients should be aware of possible adverse events with any medication, Klonoff said, but he believes that the findings provide strong evidence that GLP-1s do not increase NAION risk
Neurological consequences of obesity
Understanding these potential downsides is essential to making informed decisions about treatment and maximizing safety
This helps to prevent acid reflux during the night
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