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This is not a secret loophole
GLP-1 RAs regulate immune cell signaling, suppress proinflammatory cytokines (including tumor necrosis factor alpha (TNF), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)), enhance anti-inflammatory cytokines (interleukin-10- (IL-10)), and decrease reactive oxygen species
& Furlong, M
Available at: [Accessed 25 July 2026]
Berberine also has notably poor oral bioavailability, meaning your body absorbs very little of what you swallow
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