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At week 72, the clinical data showed that 36.8% of patients receiving semaglutide achieved fibrosis improvement without worsening of NASH and 62.9% achieved NASH resolution without worsening of fibrosis, compared with 22.4% and 34.3%, respectively, in the placebo group (Sanyal et al., 2025)

To determine how it compared with previously available doses, the higher-strength dose was tested against the 2.4 mg dose of semaglutide and a placebo

If pancreatitis is suspected, semaglutide should be discontinued and appropriate management initiated