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(PubMed) Vermeiren S, Vella-Azzopardi R, Beckwee D, et al

Second, with any short-term agent, durability is the weak point short-term weight loss is common, but the majority of patients regain weight over the following years unless the underlying behavior and physiology are addressed

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GHSR-1a undergoes receptor internalization and downregulation with repeated agonist exposure

Understand Your Dose: Wegovy typically starts at 0.25mg weekly, gradually increasing to 2.4mg over several months