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doi:10.1371/journal.pone.0103982 Chiang KC, Sun CC, Chen MH, Huang CY, Hsu JT, Yeh TS, Chen LW, Kuo SF, Juang HH, Takano M et al (2016) MART-10, the new brand of 1alpha,25(OH)2D3 analog, is a potent anti-angiogenic agent in vivo and in vitro
Specifically, alterations in phenylalanine, tyrosine, tryptophan, and histidineamino acids involved in dopamine synthesishave been implicated in the pathogenesis of SCZ, contributing to hypodopaminergic state (Karahalil et al
Gene-level modulation: Pickart & Margolina 2018 documented activity across ~4,000 human genes, with fibroblast expression patterns shifting closer to younger cells
Overall these results confirm that FOXO4-DRI promotes apoptosis in senescent endothelial cells by inhibiting FOXO4-P53 binding and phosphorylating P53
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