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In medical weight-loss programs different complimentary treatments are often used together, for example GLP-1 medications are highly effective at suppressing appetite, which can sometimes lead to fatigue and low energy from reduced caloric intake

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Rapid weight loss may theoretically influence sex hormone levels and body image, which could indirectly affect libido

First, by enhancing fatty acid transport into the mitochondria, it theoretically ensures that a greater proportion of the energy deficit is filled by fat oxidation rather than muscle protein breakdown