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Secondary outcome measures were acute myocardial infarction (ICD-10: I21), stroke (cerebral infarction or nontraumatic intracerebral hemorrhage) (ICD-10: I61, I63), or acute heart failure (ICD-10: I50.21, I50.23, I50.31, I50.33, I50.41, I50.43, I50.811, I50.813)

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This benefit is especially significant for those with insulin resistance or prediabetes