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In the 72-week non-diabetic obesity trial, adults lost -15.0% at 5 mg, -19.5% at 10 mg, and -20.9% at 15 mg. Real-world outcomes vary because dose reached, adherence, and baseline state vary
A.IwakuraT.MotrapuM.KuangM.et al (2023)
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a subsequent Phase II human clinical investigation is currently ongoing, with 592 patients enrolled and an 11-arm characterization of the molecule
PloS One 6, e24479
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