glp-1 therapy for diabetes Receptor Agonists as Treatments Type 2 GLP-1 Therapy for Weight Loss

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Clinical trial data showed patients taking oral Wegovy lost an average of 13.6% of body weight at 71 weeks, while comparable injectable GLP-1 trials have shown average weight loss to be between 15% to 20%

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This phenomenon might be noticeable in the first few weeks of treatment or after dose increases, though this mechanism has not been specifically studied in GLP-1 clinical trials

In a prospective open-label pilot study by Krajnc et al., patients had chronic IIH under treatment (some had persistent papilledema ~ 70% at baseline) [27]