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Variants in genes regulating cysteine metabolism, glutathione synthesis, and detoxification enzyme function may provide context for individual glutathione capacity and supplementation responsiveness

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Acknowledgements Not applicable Funding This study was supported by the Funding by Science and Technology Projects in Guangzhou (Grant Number: 202201020081)

Regular monitoring of inflammatory markers, disease activity scores, and functional status remains essential regardless of concurrent GLP-1 use

Note: GLOW has no trial-established dose that combines the three compounds