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These safety concerns and inadequate data have led to countries such as Singapore, European Union and many African nations to ban skin lightening treatments 1
Reference: GLP-1 receptor agonist use and overall survival among women with type 2 diabetes and breast cancer: a retrospective cohort study - (
GLP-1 is subsequently rapidly inactivated by dipeptidyl peptidase-4 (DPP-4) with a half-life of 1-3 minutes
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Exposure to greater than 25 mg may precipitate a hypertensive crisis , marked by a rapid rise in blood pressure (often exceeding 180/120 mmHg), chest pain, and acute confusion
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