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These effects were considered clinically relevant and may guide the targeted use of GLP-1RAs in managing conditions associated with inflammation and oxidative stress
Physical activity during daylight hoursparticularly morning or midday exerciseenhances sleep quality and may counteract semaglutide-related restlessness
Semaglutide contributes to weight reduction (typically 3-6 kg on average with doses used for type 2 diabetes), which decreases cardiac workload and improves metabolic parameters
Waltham, MA: UpToDate (2017)
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