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These medications are contraindicated in pregnancy, and women of reproductive age should use reliable contraception, with tirzepatide requiring additional barrier methods for 4 weeks after dose changes
This contributes to both its healing properties (maintaining blood supply to injured tissue) and its protective effects against various forms of organ damage
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Importantly, current guidelines stress that AOMs should be prescribed as part of a comprehensive weight management program that includes dietary counseling, physical activity, behavioral therapy, and regular monitoring
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