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A similar mechanistic study on ultraviolet-damaged skin cells found that 5 uM of sulforaphane induced the expression of Nrf2 target genes including NQO1 at 1.5 times the normal rate, which led to a significant reduction of sunburn damage in the cells

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4 Diagnostic approach for long-chain fatty acid oxidation disorders 4.1 Laboratory testing When a patient is suspected of having an lcFAOD based on clinical signs and symptoms, the first laboratory test of choice is measurement of acylcarnitine levels in blood

Throughout this review, mechanistic insights derived from cellular and animal models are discussed separately from translational observations and human clinical or observational data