Common side effects like nausea, fatigue, and digestive changes are real but typically temporary, and the dose-escalation approach is specifically designed to minimize them

Abbreviations ACAT: Acyl-CoA Cholesterol acyl transferase ALP: Alkaline Phosphatase ALT: Alanine Aminotransferase AST: Aspartate Aminotransferase BMI: Body Mass Index CBC-Diff: Complete Blood Count with Differential Count CRP: C-reactive Protein CT: Computerized Tomographic FBS: Fasting Blood Sugar FFM: Fat Free Mass GSH-Px: Glutathione Peroxidase GSSR: Gastrointestinal Symptom Severity Rating Hba1c: Haemoglobin A1C HDL: High Density Lipoprotein HMG-CoA: 3-Hydroxy-3-Methylglutaryl-Coenzyme A HOMA-IR: Homeostatic Model Assessment for Insulin Resistance IL: Interleukin IPAQ: International Physical Activity Questionnaire LDL: Low Density Lipoprotein MDA: Malondialdehyde MET: Metabolic Equivalent Task MRI: Magnetic Resonance Imaging MS: Metabolic Syndrome NAFLD: Non-Alcoholic Fatty Liver Disease NASH: Non-Alcoholic Steatohepatitis NF-: Nuclear Factor Kappa PNPLA3: Patatin-Like Phospholipase Domain Containing 3 PP: Pomegranate Peel PPAR: Peroxisome Proliferator-Activated Receptor Gamma RCT: Randomized Clinical Trial SOD: Super Oxide Dismutase TC: Total Cholesterol TG: Triglyceride TNF-: Tumor necrosis factor References Sheka AC, Adeyi O, Thompson J, Hameed B, Crawford PA, Ikramuddin S

For most, the weight returns quickly, typically within the first 3 to 6 months
Protein intake is particularly important, with 1.01.2 grams per kilogram body weight daily recommended to preserve lean muscle mass
GLP-1 drugs: Implications for employer health plans