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While you can supplement with a bit more than this (many supplements have 15 to 30 mg), you should not exceed the tolerable upper intake of 40 mg per day from food and supplements combined, unless supervised by a doctor

Typical weightloss results on semaglutide, tirzepatide, and others Although typical weight-loss results on semaglutide, tirzepatide, and other GLP-1 medications can vary, both semaglutide and tirzepatide have been seen to help provide meaningful average weight loss

Clinical trials have demonstrated efficacy for up to two years, but optimal treatment duration balancing benefits against cumulative adverse effect risks has not been definitively established

Experientia (1993) 49(12):10847.10.1007/BF01929917 40 JoshiPCGrayTAKeaneTC

Approximately 50% of patients achieved AHI reductions to levels where positive airway pressure therapy would no longer be required