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Pathogenesis: A change in the gallbladder epithelium that can be induced by inflammation and unknown factors

Biomarkers for endothelial function, insulin sensitivity, intracellular signaling, maintaining DNA integrity , inflammation, metabolic flexibility, mitophagy (recycling old and damaged mitochondria) and cellular senescence (also called "zombie cells" as these cells have lost proper function, harm nearby cells and do not die off) are all favorably affected

Some patients benefit from weekly therapy during high-stress seasons, while others transition to monthly treatments for maintenance

In one study, people who slowly tapered off the meds over the course of nine weeks were able to continue losing weight during the tapering period

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