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No signup required to use calculator Sync to any calendar app Retatrutide is a triple-agonist peptide (GLP-1, GIP, glucagon) that produced 28.7% weight loss in Phase 3 at 68 weeks

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Tirzepatide appears to provide greater weight loss for many people, while semaglutide has a longer track record and proven heart benefits

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Neither tesamorelin nor retatrutide has an established safety profile in pregnancy or breastfeeding