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A., Torgerson, S., Hayashi, P., Ward, J

it is the product of one of the most metabolically active processes in the human body

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120 In myeloid cell-specific SIRT1 knockout mice, lipid toxicity or LPS stimulation induced more severe hepatic inflammation, elevated pro-inflammatory cytokine levels, and enhanced M1 macrophage polarization, highlighting the critical role of SIRT1 in preserving immune balance