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Research has linked oxidative stress and glutathione depletion to: Insulin resistance Accelerated brain aging Increased risk of cardiovascular events Cellular senescence (damaged cells that dont die off) Simply put, when your antioxidant defenses go down, inflammation goes up and disease takes hold
Likewise, NADPH is necessary for many reductive biosynthetic pathways including those generating fatty acids, nucleotides, and amino acids, all of which are also necessary for growth, survival, and proliferation 12,86
A., Gough, L
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The concentration of GSH can be determined either as an endpoint read of the color developed at 405 nm or by measuring the rate of color development at 405 nm
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