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Description

Incretins (GLP1 r agonists and dual, triple agonists) and the liver. Journal of Hepatology (2023)

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Tang, C.-H

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This was attributed mostly to the gastric physiology, causing formulation dilution in the presence of additional fluid as well as fast transit of liquids into the duodenum, where peptides liable to proteolytic degradation such as the one used in this study showed a negligible absorption, potentially also due to a lower permeation-enhancing capability of CHONAC in the duodenal region

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GLP agonists may initiate weight loss, but not maintain it (206)

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