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Summary: GLP-1 receptor agonists are not licensed for NAFLD treatment in the UK but may reduce liver fat and improve metabolic parameters when prescribed for type 2 diabetes or weight management in eligible patients with concurrent liver disease

The best time to inject is 30 to 45 minutes before bedtime, on an empty stomach, ideally 2 to 3 hours after your last meal

Additionally, it occupies GIP receptors and mimics the action of the GIP hormone to enhance insulin release and promote fat breakdown

It plays a crucial role in postprandial glucose regulation and satiety signaling that is entirely separate from the incretin system

It is important to distinguish between therapeutic appetite reduction and nausea-induced food aversionthe former is desirable, while the latter may require dose adjustment or supportive management