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Animal experiments have shown that rats treated with IGF-1 LR3 (0.3 mg/kg/d) for 8 consecutive weeks have a 2-fold increase in fasting insulin levels and a 1.8-fold increase in HOMA-IR index
Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer
Nucleotide biosynthesis The de novo synthesis of purine nucleotides proceeds from R5P in a 10-step pathway to produce inosine monophosphate (IMP), which is subsequently metabolized to AMP and GMP
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