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Discussion Currently, while traditional anti-tuberculosis therapies, such as the standard first-line regimen (isoniazid, rifampicin, pyrazinamide, and ethambutol), have been effective in treating drug-susceptible TB, they face significant challenges, including drug resistance, adverse effects, and prolonged treatment durations [1]
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Even a small increase in body weight can significantly increase joint loading during walking.Second, adipose tissue produces inflammatory mediators called adipokines , which can accelerate cartilage degeneration and joint inflammation
These steadier drug levels may result in less pronounced effects on gastric emptying and reduced stimulation of nausea pathways
Sources : Nutan.net , FDA guidelines on transdermal products, cosmetic regulatory databases
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