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No published study has linked it to tumor promotion, but if you have an active malignancy, the theoretical risk of feeding blood vessels to a tumor is worth taking seriously
BPC-157 exerts its regenerative effects in part by modulating growth factor pathways, leading to enhanced tissue remodeling and angiogenesis. Sikiric et al., Current Pharmaceutical Design 2
thus, therapy is not recommended in these populations
The reduction in antioxidant capacity, along with impaired neurogenesis, has the potential to exacerbate nerve damage (Timme-Laragy et al
It also upregulates growth factors, modulates inflammatory cytokines, activates FAK-paxillin signaling (which drives cell migration into injury sites), and supports collagen synthesis
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