Self-monitoring at home should include: Weight tracking : Weekly weigh-ins at the same time of day, recorded in a diary or app, help identify trends whilst avoiding obsessive daily fluctuations Blood glucose monitoring : Patients with diabetes should test as advised by their healthcare team, typically including fasting and pre-meal readings, with increased frequency during dose adjustments Symptom diary : Recording side effects, appetite changes, and general wellbeing helps identify patterns and informs clinical discussions Dietary and activity logs : Tracking food intake and physical activity provides context for weight and glucose changes Clinical monitoring typically follows this schedule: 46 weeks : Initial review to assess tolerability, side effects, and early response
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Moreover, it is prohibited for pregnant women, those in the lactation period, and patients with severe chronic diseases
Dose Adjustment : If fatigue is severe or persistent, healthcare providers may consider slowing the dose-escalation schedule (FDA labeling allows for flexible titration with 2.5 mg increments no more frequently than every 4 weeks) or maintaining a lower maintenance dose that balances therapeutic benefit with tolerability
PMC 6430418
