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Canadian journal of anaesthesia = Journal canadien danesthesie , 10.1007/s12630-023-02440-3
Main limitation: synergy is shown for GHRH + secretagogue classes in general, not for this exact blend in a human trial
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Initially developed for type 2 diabetes, GLP-1RAs have demonstrated robust weight loss in randomized controlled trials and real-world settings, leading to their repositioning as cornerstone obesity treatments ( Human metabolic studies consistently show that reductions in energy intake account for most of the weight loss observed during GLP-1RA therapy, whereas increases in resting energy expenditure are modest or absent ( Beyond total weight loss, the quality of weight loss has become an increasingly important clinical concern
This means patients grew new, potentially fine hairs that added density but not necessarily the visual "fullness" patients expect
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