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Creatine supplementation may support muscle preservation during GLP-1 therapy, with evidence suggesting modest benefits for strength and lean mass retention

(6) Ipamorelin promotes the secretion of growth hormone and mimics ghrelin , a gut hormone known as the hunger hormone, which stimulates the speed with which food is digested , fat removed, and growth hormone released

GLP-1 Effects on BMI & Body Weight What Research Shows GLP-1 receptor agonists have been studied extensively, and the results are very consistent

A clinician decides medication

Corrado advises working with an experienced provider on dose adjustments: While clinical trials often increase doses every four weeks to the maximum, many real-world patients achieve meaningful results with slower adjustments and without ever reaching the highest dose. Talk to your doctor about whether these medications make sense for you