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The gradual accumulation to steady state over 4 weeks necessitates a structured dose-escalation protocol
But doctors should use standard questionnaires to screen all patients for restrictive eating disorders, which are both common and underdiagnosed in higher-weight people
Clinical studies show that gradual dose increases support steady fat loss over several months, with major progress between 36 months and full results often appearing after about a year of consistent use plus lifestyle changes
It has a very short half-life, requiring frequent (often daily) injections to maintain elevated GH pulses [3][4]
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