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Why Mechanism Does Not Guarantee Clinical Results Mechanistic findings are useful for hypothesis-building, but clinical outcomes require human studies with defined populations, formulations, controls, durations, and endpoints
The Argentine example inspired similar efforts elsewhere in Latin America and in a few countries in Africa and Asia
All applications are restricted to non-clinical experimental contexts
Time trends in prevalence of chronic diseases and multimorbidity not only due to aging: data from general practices and health surveys
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