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In ALS, reduced astrocytic EAAT2 levels and altered microRNA regulation (e.g., increased miR-218 and decreased miR-124a) result in the accumulation of EAAT2-derived toxic species, accumulation of glutamate, and motor neuron degeneration
Moreover, IBD patients exhibited lower prevalence of nausea, vomiting, and diarrhea, but increased rates of constipation (11%) in comparison to the general population (103)
29 The current study demonstrated that individuals with obesity more frequently used GLP-1RA medications compared with insulin (14.0% vs
Background and aims: The endothelial glycocalyx plays a key role in microvascular function
Cardiovascular markers: Reductions in non-HDL cholesterol and systolic blood pressure were observed, suggesting broader metabolic benefits beyond weight loss
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