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This alteration is accompanied by an increase in the production of cytokines, such as tumor necrosis factor (TNF-), and the interleukins IL-1, IL-6 and IL-8

Diabetes Care, 43 ,

It is important to highlight that their effects on differentiation are often context- and timing-dependent and may vary on hMSC derived from different sources (Tables 1 and 2)

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Adverse reactions related to hypotension (hypotension, orthostatic hypotension, and decreased blood pressure) were reported in 1.3% of semaglutide-treated patients versus 0.4% of placebo-treated patients during clinical trials of the semaglutide injection for weight management