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Increased serum GH and IGF1 produce feedback loops that lead to inhibition of GHRH, release of somatostatin, and consequently inhibition of GH secretion from the pituitary

Because the metabolic foundation was never rebuilt, appetite returns, dysbiosis persists, SCFAs remain low, and circadian signals remain disrupted

A common intermittent fasting plan might restrict eating to between 7am and 3pm, with the remaining 16 hours spent fasting. 3

It is a sequence of regulatory steps, each with its own timeline

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