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The primary antibodies used are as follows: P53 (Proteintech, 60283-2-Ig), pSer46-P53 (CST, 2521), FOXO4 (Proteintech, 21535-1-AP), Ki-67 (D3B5) Rabbit mAb (Alexa Fluor 647 Conjugate) (CST, 12075), P21 (CST, 14074), -H2AX (Abcam, ab2254)
CJC-1295 appears to be a synthetic analog made of the first 29 amino acids from the GHRH sequence, which has additional modifications, including the replacement of four amino acids in its structure and the attachment of a Drug Affinity Complex (DAC) to potentially extend the pharmacokinetics of the peptide
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Combined, the three compounds address three levels of biology: GHK-Cu at the gene expression level, BPC-157 at the vascular and growth factor level, and TB-500 at the structural and cellular migration level
Differential expression of glucose transporters in normal and pathologic thyroid tissue
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