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Tobin DJ
Intravenous: Used in one pilot study but not recommended for mental health applications and requires medical supervision
No participants developed antidrug antibodies
Some recent work aimed to develop tamoxifen analogues that can bypass CYP2D6 metabolism and use the esterase enzymes to produce the active metabolites to ensure equal clinical outcomes for all patients [66,67,68]
In fact, it requires a large contribution of methyl groups
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