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Sawicka, et

PubMed Central , Endocrine , vol

For instance, manoalide and trabectedin have been shown to induce Fe overload by modulating the Nrf2/SLC7A11 axis, thereby triggering ferroptosis in lung cancer cells [90, 91]

As many naevomelanocytes in cutaneous naevi show activating mutations in the BRAF or in the NRAS intracellular signalling pathways which mediate cell proliferation and differentia-tion [11, 34, 42], naevi are considered by many to be benign naevomelanocytic neoplasias

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