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Of participants, 81.8% of adults using tirzepatide lost at least 5% of their body weight compared with 66.5% of those using semaglutide
639 Despite early study termination (clinical hold) by the US Food and Drug Administration, fulranumab treatment resulted in dose-dependent efficacy and was generally well tolerated
Full inclusion and exclusion criteria are provided in the Supplementary Information
Vitamin B-12 is not intended for human use
During a median of 3.4 years of follow-up, primary outcome events occurred in 14.8% of semaglutide and 13.9% of placebo recipients, respectively, in those with baseline SGLT2i use
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