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Specifications: Unit Size: 100mg (lyophilized powder, single vial) Molecular Weight: ~340.8 Da Form: Lyophilized powder Storage: Store lyophilized powder in a cold, dry, dark environment
Maintain sterility - Using sterile solvents and technique prevents contamination
Please consult your doctor if you are undergoing treatment for any condition before taking this product
Encouraged by the gain-of-function from Glu72Arg, we searched for additional mutations enriched during the evolution of X(PC4) phages on the GD_M substrate (Supplementary Table 5) with the goal of improving activity so that proteolysis would be detectable in mammalian cells
Following FOXO4 displacement, the released p53 undergoes nuclear export and mitochondrial translocation, activating the intrinsic apoptosis pathway via BAX upregulation and BCL-2 downregulation, culminating in caspase-3 cleavage and apoptotic cell death
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