Interestingly, studies have shown that the antioxidant activity of this compound has a circadian rhythm, having antioxidant properties when it is in the dark but pro-oxidant properties when it is in the light (Gadacha et al., 2009)
GLOBAL GLUTATHIONE MARKET SIZE, BY SKIN WHITENING, BY REGION, 2018-2032 (USD MILLION) TABLE 18
GLP-1 RAs and thiazolidinediones showed favorable outcomes with GLP-1 RAs [53]
Taken together, these data suggest that SFN has a pro-oxidative effect on untransformed human T-cells leading to an increase of ROS levels and depletion of the ROS-scavenger GSH
The set of candidate SNPs that yield high radioresistance could be identified, making the use of targeted gene editing technologies (e.g., CRISPR/Cas9) to replicate those SNP variants in individual humans possible (181, 182)