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Kidney Dysfunction: While the kidneys do not directly excrete vitamin B12 efficiently, impaired renal function may lead to elevated serum B12 levels by reducing the clearance of B12-binding proteins or altering their metabolism, thereby contributing to B12 accumulation 8

Rise UP-B12 Injection is generally safe and does not usually cause any common side effects

This means that unexplained, persistent high B12, especially when it is not caused by supplements, should not be ignored