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The execution of pyroptosis, mechanistically, relies on gasdermin protein family members (160)
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When the brain is exposed to a certain degree of oxidative stress, glial cells can cause neuronal damage, but also secrete a large amount of neuropeptides to protect both glial cells and neurons, and improve the brains defense against oxidative stress (Toledano et al., 2016), so the protection of glial cells can be considered directly related to nervous system protection
Signal mining and statistical analysis Disproportionality analysis serves as a crucial tool for pharmacovigilance to identify potential drug-event safety signals 23
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