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Quick Reference: Standard Protocol Standard protocol: 250 mcg of each peptide, subcutaneous on empty stomach, AM and/or PM

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In PIONEER 8, duration of diabetes, body weight and total daily insulin dose appeared to be higher in patients receiving basal-bolus insulin than in those on the other insulin regimens

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Who May Be Considered for Dual-Agent Therapy (Red Flags) Candidates for tirzepatide-phentermine combination are exceptionally rare and typically have failed monotherapy with documented weight loss plateaus despite dose optimization