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The study included people with cirrhosis, or scarred and permanently damaged livers
Jastreboff and colleagues studied the obesity Phase 2 in NEJM observing mean body weight reduction reaching approximately 24 percent at the 12 mg dose tier at 48 weeks (PMID 37366315)
They often improve rapidly after eating
This suggests that the mechanism of glucose uptake might involve additional cellular processes beyond the traditional receptor binding
Its multifaceted mechanism of action not only improves glycemic control but also facilitates substantial weight loss and offers potential cardiovascular and metabolic benefits
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