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Available from: Cinemre H, Serinkan Cinemre BF, ekdemir D, Aydemir B, Tamer A, Yazar H
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Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy
The schematic representations refer to the inhibitors that belong to: a-d) Kunitz family (BPTI-type), e-i) Kazal family (PSTI-type), j) inhibitor from Streptomyces, k) Kunitz-type family from soybean, l) Bowman-Birk family, m) potato type I family, n) potato type II family Cysteine residues in homologous proteins (those of common ancestry) are very conservative according to PAM 250 scoring matrix (Fig 4)
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