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The AACE/ACE guidelines note that selecting between agents should consider patient preference for injection frequency, cost and insurance coverage, tolerability history, and whether a dual GIP/GLP-1 mechanism (tirzepatide) offers incremental benefit for an individual patient's metabolic profile [19]

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his doctor recommended the weekly shot to control his blood sugar

This is no longer a niche question for diabetics or the severely obese

Others notice increased sleep disturbances , though the direction varies, with some sleeping better and others worse