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In humans, dietary l-carnitine is converted into the atherosclerosis- and thrombosis-promoting metabolite TMAO via 2 sequential gut microbiotadependent transformations: (a) initial rapid generation of the atherogenic intermediate BB, followed by (b) transformation into TMA via low-abundance microbiota in omnivores, and to a markedly lower extent, in vegans/vegetarians
World Psychiatry 15 , 288289 (2016)
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NRF2 is a member of the cap n collar (CNC) subfamily of the basic region leucine zipper (bZIP) transcription factors, involved in multiple cellular processes [130,131,132,133,134,135]
Targeted Nutrition : Specific compounds like phosphatidylserine (100 mg three times daily) directly lower cortisol levels by improving feedback mechanisms in the brain
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