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In the SURMOUNT-1 trial the highest dose produced about 20.9% mean weight loss over 72 weeks
Key benefits are: It helps reduce body weight by lowering appetite, controlling cravings, and prolonging the feeling of fullness after meals
Losing weight can be an effective way to improve your sleep quality
Glucagon suppression They inhibit glucagon release from pancreatic alpha cells, reducing hepatic glucose production
The guideline explicitly states: "Clinicians should screen for depression, anxiety, and disordered eating behaviors before initiating and during pharmacotherapy for obesity in adolescents" [19]
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