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The New England Journal of Medicine, 10.1056/NEJMoa2511774
Concurrently, SPP1 TAMs amplify immunosuppressive signals, collectively fostering an immune-exclusion niche that blunts ICB efficacy
Patients often describe it as finally unlocking the last five percent helping them feel lighter tighter and more in control of cravings without the heavy or sluggish sensation associated with full therapeutic doses
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Patients should know the symptoms (nausea, vomiting, abdominal pain, fast breathing) and be told when to pause the medication
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