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Valentino K, Teopiz KM, Cheung W, Wong S, Le GH, Rosenblat JD, et al
This significant unmet clinical need underscores the urgency for developing adjunctive or alternative neuroprotective strategies
The schedule mirrors the clinical-trial protocols that drove significant weight loss up to 24% at 48 weeks on 12 mg weekly [2] while holding gastrointestinal effects down through gradual escalation [1] [4]
Most gastrointestinal side effects improve within one to two weeks as your body adapts, but some patients genuinely require a permanent lower dose
In certain instances, modifying the dosage or changing medication can be required
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